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Updated: Feb 10, 2026

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系统性红斑狼患者的罕见TRAF5编码变异通过内皮功能障碍加剧肺高血压

Xiaoyue Deng1,2,3,4, Tianyi Yuan5, Junyan Qian1,2,3,4

  • 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Innovation (Cambridge (Mass.))
|February 9, 2026
PubMed
概括

罕见的TRAF5基因变异与系统性红斑狼 (SLE) 患者的肺动脉高血压 (PAH) 有关. 缺少TRAF5会损害内皮细胞功能,恶化SLE-PAH,并提出新的治疗点.

关键词:
这是SLE-PAH.在TRAF5中,TRAF5是指TRAF5.在WES WES中,您可以使用内皮质功能障碍 内皮质功能障碍遗传变异是一种遗传变异.肺血管重塑 肺血管重塑

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