探索重复的低水平红光疗法在延缓儿童近视进展方面的疗效:最新的系统性审查和元分析
Chen Liu1, Yating Zhou2, Zongyue Zhan3
1Department of Ophthalmology, Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning, China.
Frontiers in medicine
|February 9, 2026
概括
重复的低水平红光 (RLRL) 治疗显著减缓了儿童近视的进展. 这种疗法提供了一种非药物治疗方法,用于治疗儿科患者近视.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 公共卫生 公共卫生
背景情况:
- 儿童近视是一种日益严重的公共卫生问题.
- 低水平红光疗法 (RLRL) 正成为一种非药物干预.
- 需要对儿科近视的RLRL进行基于证据的评估.
研究的目的:
- 系统地审查和元分析RLRL治疗的疗效.
- 评估RLRL对儿科近视进展的影响.
- 提供RLRL在儿童的治疗用途的证据.
主要方法:
- 进行全面的数据库搜索 (PubMed,科学网,Embase,中国数据库) 到2025年5月.
- 包括符合特定标准的随机对照试验 (RCT).
- 使用Stata v18.0进行的元分析,共有1053名参与者 (515名RLRL,538名对照).
主要成果:
- 在RLRL组中,球体等价 (SER) (SMD=0.84) 和轴长 (AL) (SMD=-1.01) 显著减少.
- 随着RLRL治疗而显著增加亚叶胆道厚度 (SFChT) (SMD=0.81).
- 在元分析中没有发现重大出版偏差.
结论:
- 作为标准治疗的辅助剂,RLRL治疗显著减缓了儿童近视的进展.
- 这些发现支持RLRL作为小儿近视的有效治疗选择.
- 进一步的研究可能会探索长期结果和最佳RLRL参数.
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