印度次大陆职业癌症的系统审查
Reena Bhardwaj1, Neeraj Kumar2, Swati Joshi3
1Epidemiology and Biostatistics, Indian Council of Medical Research-National Institute of Child Health and Development Research (ICMR-NICHDR), New Delhi, IND.
Cureus
|February 9, 2026
概括
印度的职业致癌物暴露与各种癌症有关,包括淋巴瘤和肺癌,特别是在农业和家庭工人中. 需要更多的研究来评估风险,并有效监测工作场所的危险.
科学领域:
- 职业健康 职业健康 职业健康
- 公共卫生 公共卫生
- 癌症研究 癌症研究
背景情况:
- 职业接触致癌物 (化学品,金属,尘埃,有机物质) 是各行各业的重大公共卫生问题.
- 了解印度工作场所暴露与癌症风险之间的联系对于有针对性的干预至关重要.
研究的目的:
- 系统地审查印度有关职业癌症的现有文献.
- 确定工人接触到的致癌物种,并确定研究缺陷.
主要方法:
- 在多个数据库 (PubMed,Ovid,Cochrane,Google Scholar) 和参考列表中进行了系统的搜索.
- 包括2000年1月1日至2024年10月31日期间以英语出版的研究,重点关注印度职业致癌物暴露.
- 从六项符合条件的研究 (12,360名患者) 中提取了数据,并进行了主题分析.
主要成果:
- 六项研究符合纳入标准,揭示了职业暴露与癌症风险之间的关联.
- 特定的工人群体 (杀虫剂工人,农民,家务工人,贝迪工人,农业工人) 患有淋巴瘤,食道状细胞癌,肺癌,宫癌,口腔粘膜癌和胃肠道癌等癌症的风险增加.
- 在了解印度职业癌症风险的全部范围方面,存在重大研究差距.
结论:
- 有必要进行更多的原始研究,采用代表性的工人样本,以准确评估印度的职业癌症风险.
- 在印度对职业致癌物的系统监测对于危害控制和指导未来研究工作至关重要.
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