糖尿病药物停用问卷的开发,验证和应用:一个多中心观测研究
Vivek Agarwal1, Mukulesh Gupta2, Rajiv Awasthi3
1Endocrinology, RR Diabetes and Heart Care Centre, Lucknow, IND.
大约25%的糖尿病患者停止服用抗糖尿病药物,通常是长时间服用. 这项研究引入了一个新的问卷来评估停产,揭示了知识差距和访问问题作为关键驱动因素.
科学领域:
- 内分泌学和新陈代谢学
- 公共卫生 公共卫生
- 制药科学 制药科学
背景情况:
- 药物坚持对于控制糖尿病至关重要,但停药会带来重大风险,例如代谢失补偿.
- 停用抗糖尿病药物是很难理解的,缺乏标准化的定义和评估工具.
研究的目的:
- 开发和验证一个文化适应的,自我管理的调查问卷,用于评估抗糖尿病药物停用.
- 确定北印度人口中药物停药的患病率,持续时间和相关因素.
主要方法:
- 印度北部的一项多中心观测研究,涉及747名成人糖尿病患者.
- 开发和心理测量验证一个结构化,自我管理的问卷.
- 评估戒断模式和影响因素.
主要成果:
- 25.3%的参与者报告说已停止服用抗糖尿病药物超过七天,许多发作持续数月至一年以上.
- 停药与较高的HbA1c (约. 0.5%更高),禁食和食后葡萄糖水平.
- 停药的主要原因包括药物不可用,对低血糖的恐惧,良好的血糖控制和认为药物不必要的信念.
结论:
- 停用药物是糖尿病护理中普遍存在的问题,影响了大约四分之一的患者,通常是长时间的.
- 现在可以使用一个验证的问卷来可靠地评估在印度停止服用抗糖尿病药物的情况.
- 干预措施应解决患者教育问题,并利用数字依从支持系统来打击戒断,重点关注知识和获取障碍.
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