相关实验视频
Updated: Feb 10, 2026
07:30
Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
4.4K
药物诱导的精神病:移植后的剧烈转变
Dalal A Obaid1, Maryam AlJasmi2, Khawla Y Alawadhi3
1Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, ARE.
Cureus
|February 9, 2026
概括
在移植患者中,药物诱导的精神病甚至在治疗性塔克罗利斯水平下也可能发生. 早期识别和多学科管理是恢复的关键,而不会影响移植的生存.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 药物诱导的精神病是固体器官移植接受者的罕见但严重的并发症.
- 经常涉及卡尔西纽林抑制剂,如塔克罗利斯,在治疗水平上可能发生毒性.
- 皮质类固醇的使用可能会加剧神经精神疾病的副作用.
研究的目的:
- 报告脏移植接受者的药物诱导精神病病例.
- 要突出诊断挑战和管理策略的这种条件.
- 强调在新发精神病的移植患者中考虑神经毒性的重要性.
主要方法:
- 一个34岁的男性脏移植接受者的病例报告.
- 临床表现,实验室发现和药物 anamnesis 被审查.
- 管理涉及多学科的方法,调整免疫抑制和启动抗精神病治疗.
主要成果:
- 患者出现了严重的精神病症状,包括幻觉和妄想.
- 塔克罗利莫斯的水平处于治疗范围之内,这表明尽管水平看似正常,但有潜在的毒性.
- 普雷德尼索隆的使用可能导致了精神病.
- 随着普得尼索隆的停止和抗精神病治疗,症状有所改善,而塔克罗利斯的治疗仍在继续.
结论:
- 移植患者的新发性精神病需要高度怀疑氨酸抑制剂的神经毒性,即使治疗药物水平.
- 多学科的方法对于管理神经精神疾病并发症,同时保持移植功能至关重要.
- 早期识别和干预对于改善结果和减少发病率至关重要.
相关概念视频
01:28Psychosis and Antipsychotic Drugs: Overview
922
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
922
01:28Kidney Transplant I: Introduction
494
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
494
01:26Kidney Transplant II: Surgical Procedure
436
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
436
01:16Kidney Transplant III: Nursing Management
405
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
405
01:45Kidney Structure
75.5K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
75.5K
01:26Psychosis: Goals of Pharmacotherapy
543
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
543