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尿液分析作为尿路感染的可靠指标:一个横截面研究
Zaraq R Khan1, Zeeshan Ullah2, Adel Alwakeedi1
1Infectious Disease, University of Louisville Hospital, Louisville, USA.
Cureus
|February 9, 2026
概括
阳性尿液分析并不总是证实尿路感染 (UTI). 仅仅依靠尿液检测可以导致过度诊断和不必要的抗生素使用,从而导致抗生素耐药性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 尿路感染很常见,但缺乏确切的诊断标准.
- 这导致过度诊断和过度使用抗生素,培养了耐多药生物.
研究的目的:
- 评估阳性尿液分析 (≥10个白细胞/高功率场) 和确诊的尿路感染之间的相关性.
- 评估尿液分析的诊断准确性,以确定真正的尿路感染.
主要方法:
- 一项对路易斯维尔大学医疗保健网络的100名患者进行的横截面回顾性研究.
- 使用了非随机连续采样.
- 数据使用SPSS v25与描述性统计数据进行分析.
主要成果:
- 只有17%的患者符合尿路感染的操作定义,主要是女性.
- 相当一部分 (77%) 的尿路感染是无症状的.
- 一个阳性尿液分析 (≥10 WBC/HPF) 并没有始终与确定的尿路感染相关.
结论:
- 尿液分析本身就是一种不可靠的尿路感染指标.
- 应该重新考虑医院政策,建议仅基于阳性尿液分析的反射尿液培养.
- 阻止常规反射培养可以防止过度诊断,减少不必要的抗生素处方.
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