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Updated: Feb 10, 2026

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
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免疫微环境和dMMR胃癌的治疗反应:异质性和对免疫疗法的影响

Liping Wang1, Xinliang Zhong1, Mengxing Diao1

  • 1Department of Medical Oncology, Southern University of Science and Technology Hospital, Shenzhen, Guangdong 518055, P.R. China.

Oncology letters
|February 9, 2026
PubMed
概括

缺陷不匹配修复 (dMMR) 的高瘤突变负担 (TMB) 的胃癌显示出不同的免疫疗法反应. 低CD8+ T细胞和高Tregs表明耐药性,这表明个性化瘤免疫微环境 (TIME) 评估对于预测结果至关重要.

关键词:
生物信息学分析分析dMMR 是一个MMR.胃癌 胃癌 是一种胃癌.免疫系统逃脱,逃离免疫系统.免疫微观环境 免疫微环境免疫疗法 免疫疗法

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