微波除与T1bN0M0乳头甲状腺癌的手术:一种倾向性得分匹配的队列研究
Xinshu Zhao1, Peiwen Wang2, Deng-Ke Teng2
1Future Medical Laboratory, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
Frontiers in endocrinology
|February 9, 2026
概括
微波除 (MWA) 是治疗T1b乳头甲状腺癌 (PTC) 的手术的安全和有效替代方案,在局部瘤进展和没有永久并发症的无复发存活方面显示了可比的结果.
科学领域:
- 在瘤学瘤学.
- 最少侵入性的治疗方法
- 甲状腺癌治疗方法 甲状腺癌治疗方法
背景情况:
- 乳头甲状腺癌 (PTC) 是最常见的甲状腺癌类型.
- T1b阶段PTC涉及具有特定大小和甲状腺外延伸标准的瘤.
- 手术切除一直是T1b PTC的标准治疗方法,但正在探索微创的选择.
研究的目的:
- 评估微波除 (MWA) 对T1b PTC的疗效和安全性.
- 为了比较MWA结果与T1b PTC患者的手术切除.
- 评估局部瘤进展,无复发生存率和并发症率.
主要方法:
- 在2019年4月至2023年10月期间接受治疗的T1b PTC患者的回顾性分析.
- 1:1倾向分数匹配 (PSM) 来比较MWA和手术组.
- 分析局部瘤进展 (LTP),无复发生存率 (RFS) 和并发症.
主要成果:
- 在PSM后,86名患者在MWA组,86名患者在手术组.
- 在MWA (2.33%) 和手术 (3.49%) (p=0.650) 之间没有显著的LTP差异.
- MWA实现了98.53%的体积减小率,没有永久性并发症,远程转移或延迟手术.
结论:
- 微波除 (MWA) 证明了与T1b PTC.手术相比的疗效.
- 对于T1b PTC,MWA是一种安全的替代治疗选择.
- 进一步的研究可以在更大的队列中探索MWA的长期结果.
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