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Updated: Feb 10, 2026

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
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Published on: April 10, 2019

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RNA结合蛋白Imp1促进Spdef转录程序和粘液化在死性肠球炎期间

Kevin A Swift, Alexandria J Shumway, Molly Aloia

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    胰岛素样生长因子2 mRNA结合蛋白1 (IMP1) 增强了在死角 enterokolitis (NEC) 期间杯状细胞的功能和粘液的产生. 这一发现为预防NEC提供了潜在的治疗点,NEC是早产婴儿致命的胃肠道疾病.

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