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Updated: Feb 10, 2026

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利用FBXO31与终端胺基功能化分子用于向蛋白质降解

Chenlu Zhang, Xiaokang Jin, Chen Zhou

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    FBXO31是一种用于向蛋白降解 (TPD) 的新型E3酶. 它使用化学招募剂来降解目标蛋白质,扩大TPD的范围超出CRBN.

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