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Updated: Feb 10, 2026

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs
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Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs

Published on: January 27, 2023

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PRDM16协调基因和表观遗传程序,控制膝关节关节中的体生成和体细胞表型规范

Eloise Fadial, Victoria Hansen, Gulzada Kulzhanova

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    PRDM16对于软骨发育至关重要,它调节体生成和体细胞身份. 失去PRDM16会延迟骨的形成,并暗示其具有冠状动脉保护作用,通过表观遗传修饰影响关键基因.

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