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Updated: Feb 10, 2026

Genome Engineering of Primary Human B Cells Using CRISPR/Cas9
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在初级人类T细胞中功能增强剂景观的精确CRISPR注释

Ping Wang, Josephine R Giles, Hua Huang

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    研究人员开发了一种CRISPR干扰 (CRISPRi) 平台,用于绘制T细胞中的功能非编码元素. 这种方法通过精确编辑像HAVCR2这样的基因来提高抗瘤功效来增强CAR T细胞疗法.

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