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Updated: Feb 10, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
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选择性库林3环E3酶抑制剂通过双重胰岛素敏感和胰岛素otropic作用减轻高血糖

Lijie Gu, Lei Xiong, Mohammad Nazmul Hasan

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    用DI-1859准库林3 (Cul3) 脱,通过增强胰岛素敏感性和分泌改善2型糖尿病. 这种双重作用有效降低肥胖小鼠的高血糖.

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