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Updated: Feb 10, 2026

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
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Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

Published on: June 16, 2011

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EXOSC3 G191 变种触发器 全系统重新校准RNA处理机械

H R Sagara Wijeratne, Avery M Runnebohm, Monica P Barron

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    致病性EXOSC3变异导致1B型 (PCH1B) 的点脑小贝低成形. 这项研究揭示了EXOSC3 G191变种如何破坏RNA外基因组的稳定性,影响基因表达并促进疾病变异性.

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