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Updated: Feb 10, 2026

Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells
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Published on: February 25, 2007

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通过YY1介导的多组功能保护了造血干细胞免受过早衰老的影响

Sahitya Saka, Junki P Lee, Yinghua Wang

    bioRxiv : the preprint server for biology
    |February 9, 2026
    PubMed
    概括

    衰老的造血干细胞 (HSC) 表现出髓状偏差和功能丧失. 阴阳1 (YY1) 聚合组 (PcG) 活动对于维持高细胞静止和自我更新至关重要,延缓衰老.

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