芝麻-衍生氧化物纳米颗粒表现出增强的抗氧化,抗菌和伤口愈合活动
Aqsa Khalid1, Raheela Waheed2, Zermina Rashid3
1Department of Biochemistry and Biotechnology, The Women University Multan, Multan, Pakistan, wum.edu.pk.
BioMed research international
|February 9, 2026
概括
绿色合成的氧化纳米颗粒 (ZnZM NPs) 来自Zea mays叶提取物显示出强大的抗菌和抗氧化作用. 这些纳米粒子有效地加速了老鼠的伤口愈合,表明它们作为安全的纳米药物的潜力.
科学领域:
- 纳米技术纳米技术
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
背景情况:
- 感染阻碍伤口愈合,需要新的治疗方法.
- 开发有效的伤口愈合策略仍然是医学的重大挑战.
研究的目的:
- 开发和评估Zea mays叶提取物介导的氧化纳米颗粒 (ZnZM NPs).
- 评估生物合成ZnZMNP的抗菌,抗氧化和伤口愈合潜力.
主要方法:
- 绿色合成ZnZMNP使用Zea mays树叶提取物.
- 使用UV-Vis,EDX和FT-IR光谱学对ZnZMNP进行表征.
- 在老鼠模型中评估抗菌活性,抗氧化能力和伤口愈合.
主要成果:
- ZnZM NPs对大肠杆菌,P. aeruginosa和K. pneumoniae具有显著的抗菌活性.
- 这些纳米颗粒显示出显著的抗氧化特性,包括铁离子降解能力和自由基清除能力.
- 1% ZnZM NPs 的局部凝显著加快了小鼠的伤口愈合和加强了组织再生.
结论:
- 生物合成的ZnZMNP具有有前途的抗菌,抗氧化和伤口愈合特性.
- ZnZM NPs可以作为一种经济,安全和可持续的纳米药物用于临床应用.
- 这项研究强调了植物介导纳米颗粒在先进伤口护理中的潜力.
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