bensodiazepine 相关的多物质使用和老年创伤患者的医院资源利用:一项回顾性多中心研究
Constance McGraw1, William Tyler Crawley2, Christopher Zaw-Mon3
1Trauma Research, Swedish Medical Center, Englewood, Colorado, USA.
Trauma surgery & acute care open
|February 9, 2026
概括
在老年创伤患者中,使用二胺阳性多重物质与重症监护室 (ICU) 住院和输血的增加有关. 早期识别这一高风险群体对于更好的结果至关重要.
科学领域:
- 老年创伤的治疗方法
- 药物使用障碍 药物使用障碍
- 医院资源利用情况 医院资源利用情况
背景情况:
- 在50岁以上的成年人中,二胺的使用正在增加,通常与其他物质一起使用.
- 这种模式与创伤风险增加和医疗保健资源使用有关.
- 老年创伤患者与二相关的多重物质使用面临重大挑战.
研究的目的:
- 评估与二胺相关的多重物质使用对老年创伤患者医院资源利用的影响.
- 确定与该患者组相关的特定资源利用结果.
- 为高风险的老年创伤患者提供早期识别策略的信息.
主要方法:
- 在四个美国创伤中心 (2016-2022) 进行了50岁及以上创伤患者的回顾性队列研究.
- 患者被分类为使用二胺阳性多重物质 (PSB+),其他多重物质 (PSB-),或物质阴性 (SB-).
- 反向概率加权 (IPW) 用于平衡分析结果的共变量,如ICU入院,通风和输血.
主要成果:
- 该研究包括2201名患者:7%的PSB+,8%的PSB-和85%的SB-.
- PSB+患者年龄较大,更有可能是女性,并且跌倒率,酒精含量和严重受伤率更高.
- 在IPW之后,PSB+与更高的ICU入院率 (OR 1.84) 和输血 (OR 1.87) 相关.
- 对于65岁以上的患者来说,PSB+显示了ICU入院的几率超过三倍 (OR 3.35).
结论:
- 在老年创伤患者中使用二胺阳性多重物质独立地与急症室入院和输血增加有关.
- 这些发现强调了早期识别这一脆弱人群的关键需求.
- 有针对性的干预措施可以潜在地减轻不良结果并优化资源配置.
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