术前营养不良与腰部融合后的术后并发症增加有关:一种倾向匹配的分析
Ali Mehaidli1, Muaaz Wajahath2, Jad Lawand3
1Department of Orthopaedic Surgery, Henry Ford Hospital, Detroit, MI, USA.
Journal of spine surgery (Hong Kong)
|February 9, 2026
概括
手术前营养不良显著增加了腰部融合 (LF) 患者的风险,导致并发症,感染和重复手术的发生率更高. 营养评估和优化对于改善LF结果和降低医疗保健成本至关重要.
科学领域:
- 脊柱外科手术 脊柱外科手术
- 外科手术的结果
- 营养科学 营养科学
背景情况:
- 腰椎融合 (LF) 是对退行性脊柱疾病的常见程序,但它带有相当大的风险.
- 已知手术前的营养不良,以低血清白蛋白或白细胞计数为标志,会影响愈合并增加感染风险.
- 手术前营养不良对LF长期结果的影响尚不清楚.
研究的目的:
- 调查手术前营养不良和腰部融合后的长期术后结果之间的关联.
- 评估营养状况对LF后并发症率和手术成功的影响.
主要方法:
- 使用TriNetX美国协作网络 (2003-2023) 进行的一项回顾性队列研究.
- 确定了接受LF的成年患者,营养不良以血清白蛋白<3.5g/dL或白细胞计数<1,500/mm3的术前定义.
- 用1:1的倾向得分匹配来比较营养不良和营养良好群体 (n=20,693个) 在90天和5年后的结果.
主要成果:
- 营养不良患者的90天输血率,伤口并发症,感染和再入院率明显高.
- 在5年后,营养不良与伪关节炎,修复手术和压缩骨折的增加率有关.
- 矛盾的是,营养不良群体的全因死亡率较低,这可能是由于选择偏差.
结论:
- 手术前营养不良是一种独立的风险因素,增加了手术后并发症和LF后的重新手术.
- 营养不良与腰部融合后的长期手术成功率较低有关.
- 常规营养评估和优化应纳入手术前规划,以减轻LF患者的风险和改善结果.
相关概念视频
Nuclear Fusion
33.9K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.9K
Sign Test for Matched Pairs
423
The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
To conduct the sign test, we first calculate the differences in...
423
Increasing Function
400
An increasing function exhibits a rise in output values as input values increase. This behavior is depicted graphically as a curve or line that slopes upward from left to right. Such a function satisfies the condition that if x1 < x2, then f(x1) < f(x2), indicating that the function values grow with increasing inputs. This concept is fundamental in understanding growth trends across various domains, such as population dynamics, financial investments, or resource consumption.The...
400
Hemodialysis II: Procedure and Complications
928
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
928
Pneumonia III: Complications and Assessment
903
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
903
Diabetes: Symptoms, Diagnosis, and Complications
2.4K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.4K


