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1995-2024年心脏移植成年患者的生存率:RETRAC注册表的一份报告
Juan David López-Ponce-de-León1,2,3, Juan Andrés Muñoz-Ordoñez2, Alejandro Toro-Pedroza2
1Servicio de Cardiología, Fundación Valle del Lili, Cali, Valle del Cauca, Colombia.
Global heart
|February 9, 2026
概括
哥伦比亚的心脏移植 (HT) 的存活率低于全球平均水平,年轻男性的存活率更高. 慢性病 (CKD) 在HT患者中显著增加死亡风险.
科学领域:
- 心脏病学 心脏病学
- 移植医学 移植医学
- 公共卫生 公共卫生
背景情况:
- 心脏移植 (HT) 是末期心力衰竭的主要治疗方法.
- 关于拉丁美洲 (LATAM),特别是哥伦比亚的HT结果的数据有限.
研究的目的:
- 分析哥伦比亚成年患者的HT结局.
- 确定影响该地区移植后生存的因素.
主要方法:
- 从1995年至2024年使用RETRAC注册表对260名成年HT患者的回顾性分析.
- 通过卡普兰-梅尔曲线和考克斯比例危险模型评估的生存结果.
主要成果:
- 平均生存时间为7.4年;1年,5年和10年生存率分别为74.6%,56.9%和46.9%.
- 40岁以下的患者的平均存活时间最高 (8.4年),60岁以上的患者的平均存活时间最低 (2.2年).
- 慢性病 (CKD) 是死亡的一个独立风险因素 (HR=1.79,p=0.01).
结论:
- 哥伦比亚的HT患者具有可比的人口统计数据,但生存率低于国际注册.
- 结果比其他拉丁美洲研究更好,但需要区域战略.
- 慢性瘤是死亡率的关键预测因素,需要有针对性的干预措施.
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