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Updated: Feb 10, 2026

Author Spotlight: Flow Cytometric Determination of Pyroptosis in Avian Cells
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肝脏的泛膜热,由气体皮质胺编码的mRNAs诱导

Yi-Jiao Huang1, Lin Li1,2, Guan Yang3

  • 1State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, China.

National science review
|February 9, 2026
PubMed
概括

这项研究揭示了通过mRNA诱导的Gasdermin D N-terminal (GSDMD-NT) 诱导的体内热,会导致哺乳动物的急性器官损伤和死亡. 这些效应在使用特定抑制剂时是可逆的,表明了治疗潜力.

关键词:
GSDMDMD的总体发展目标是什么肝脏受损 肝脏受损 肝脏受损在 mRNA-LNP 组合中.非人类灵长类动物.热致灭 (pyroptosis) 是一种致的过程.

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