针对脑干病变的无框架与基于框架的立体活检的有效性和安全性:与无框架技术显示可比结果的比较
Marcos Dellaretti1, Franklin Faraj1, João Pedro Santos Albuquerque1
1Department of Neurosurgery, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil.
Surgical neurology international
|February 9, 2026
概括
针对脑干病变的无框架和基于框架的立体活检显示了类似的诊断产量和安全性. 这两种技术都是用于脑干瘤诊断的可行选择,基于可用的资源和专业知识提供灵活性.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 神经病理学神经病理学
背景情况:
- 脑干瘤是罕见的,异质的,并具有挑战性的手术方法.
- 立体活检对于诊断无法切除的大脑干病变至关重要.
- 在大脑干中无框架立体活检的有效性和安全性仍在争论中.
研究的目的:
- 为了比较无框架与基于框架的立体活检技术的诊断产量,安全性和并发症率.
- 在关键脑干区域评估两种立体活检方法的有效性.
- 为了确定无框架技术是否可以达到与基于框架的技术相似的结果.
主要方法:
- 追溯分析29个基于框架和17个无框架的脑干病变的立体活检.
- 组织病理学和免疫组织化学分析用于诊断确认.
- 使用SPSS,Kolmogorov-Smirnov和费舍尔测试的技术之间的诊断产量,并发症率和死亡率的统计比较.
主要成果:
- 在无框架和基于框架的技术之间,没有发现关于诊断产量,并发症率或死亡率的统计学上显著差异.
- 跨额外的外科手术方法是唯一与提高疗效 (78.3%,P=0.001) 显著相关的因素.
结论:
- 无框架和基于框架的立体活检技术都有效用于诊断脑干病变.
- 技术之间的选择取决于服务的可用性和外科医生的经验.
- 这两种方法都在为脑干病变选择活检方法时提供了灵活性.
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