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由大脑连接学辅助的雄辩的质瘤切除:一种用于清醒神经外科手术的新工具
José Luis Navarro-Olvera1, Noé Pérez-Carrillo1, José Damián Carrillo-Ruiz1,2
1Neurosurgical Service, General Hospital of Mexico "Dr Eduardo Liceaga", Mexico City, Mexico.
Surgical neurology international
|February 9, 2026
概括
本案例研究强调了在运动皮质中使用连接体引导的神经导航和清醒手术成功切除扩散性质瘤. 这种结合的方法平衡了瘤的去除与功能维护在雄辩的大脑区域.
科学领域:
- 神经外科 神经外科
- 神经瘤学神经瘤学
- 在Connectomics上,我们提供了连接.
背景情况:
- 醒着的骨切除术与手术内映射是切除雄辩的大脑区域质瘤的标准.
- 大脑连接学提供了一种基于连接的新方法,用于可视化患者特定的神经网络.
- 这项研究是拉丁美洲首个使用连接体引导的神经导航与清醒监测用于扩散性质瘤切除的病例.
研究的目的:
- 为了证明连接体引导的神经导航和醒着手术对质瘤切除的联合疗效.
- 展示一种针对患者的,基于网络的方法,用于在雄辩的大脑区域进行手术规划.
- 为了实现最大的瘤切除,同时保持神经功能.
主要方法:
- 针对患者的连接组分片,以识别瘤内的运动区域.
- 醒着的骨切除术具有手术内功能映射,以指导瘤切除.
- 手术干预根据实时功能监测进行调整,以防止缺陷.
主要成果:
- 在运动皮层中成功切除了世界卫生组织2级的扩散性星细胞瘤.
- 鉴定内口腔运动小组指导手术规划.
- 观察到过渡性单衰减,并停止了手术,在两周内完全康复.
结论:
- 连接ome引导的神经导航和清醒手术协同平衡瘤和功能目标.
- 通过绘制个性化网络,Connectomics改善了手术前的规划,即使在扭曲的大脑中也是如此.
- 这种综合方法是雄辩性质瘤安全最大切除的有希望的策略,需要进一步研究.
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