根据切除的子段数量,低衰减体积的术后变化:一个回顾性队列研究
Ryo Karita1, Hironobu Wada1,2, Yuki Hirai1
1Department of Thoracic Surgery, International University of Health and Welfare Narita Hospital, Narita, Japan.
Journal of thoracic disease
|February 9, 2026
概括
广泛的肺切除 (≥6个子段) 可能导致肺高通胀,以增加的低衰减体积百分比 (ΔLAV%) 表示. 有限的切除 (≤5个子段) 很少引起这种变化,从而保留肺膜.
科学领域:
- 胸部外科手术 胸部外科手术
- 肺部成像扫描 肺部成像扫描
- 定量CT分析 定量CT分析
背景情况:
- 细分切除术提供了有利的结果,但手术后的残留肺部变化尚不清楚.
- 低衰减体积 (LAV) 量化了肺变化,并有助于肺形态分析.
- 了解术后肺形态对于肺节省切除至关重要.
研究的目的:
- 为了研究手术后的形态变化,在肺部切除和细分切除后剩余的肺叶.
- 为了评估低衰减体积 (LAV) 与切除子段数量的关系.
- 为了确定主要肺切除后肺高通胀的预测因素.
主要方法:
- 追溯分析56名患者进行了分管切除术或分管切除术,并进行了手术前和后的高分辨率CT扫描.
- 3D重建来计算LAV和LAV百分比 (LAV%).
- 使用ROC曲线进行比较分析,以定义高通胀率 (ΔLAV% ≥0.7%) 并根据切除的子段 (≤5对≥6) 对患者进行分层.
主要成果:
- 所有患者都显示术后肺体积增加,但在残留叶中的LAV或LAV%没有显著的整体增加.
- 在 ΔLAV% 与切除子段数量 (R=0.30,P=0.02) 之间发现了微弱但显著的正相关性.
- 与≤5组相比,≥6个切除子段的组显示了LAV和ΔLAV%的显著增加,这表明过度通货膨胀.
结论:
- 切除的子部分数量与增加的 ΔLAV% 有正相关,这表明过度通货膨胀.
- 广泛的肺切除 (≥6个子段) 经常会导致剩余的肺叶的膨胀.
- 有限的切除 (≤5个子段) 很少导致过膨胀,突出显示了保留肺膜的好处.
更多相关视频
03:05Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
Published on: November 21, 2025
621
05:53Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
10.7K
相关概念视频
Transcription Attenuation in Prokaryotes
18.5K
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin structure. Bacteria use these hairpins to regulate the transcription process and control the synthesis of several amino acids including histidine, lysine, threonine, and phenylalanine. Transcription attenuation takes place in the non-coding regions of mRNA.
There are several different mechanisms used to attenuate transcription. In ribosome mediated...
There are several different mechanisms used to attenuate transcription. In ribosome mediated...
18.5K
Constant Volume Calorimetry
30.8K
Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...
30.8K
Volume of Distribution
1.3K
The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.
1.3K
Problem Solving: Volume
80
The volume of a fuel tank mounted on the wing of a jet aircraft can be modeled using the concept of solids of revolution. In this case, the tank is formed by rotating a two-dimensional region, defined by a mathematical function, about the x-axis. The region extends along the axis from zero to two meters, and the resulting three-dimensional shape is symmetric about the axis of rotation. Because the boundary curve lies directly against the axis, the disk method is an appropriate technique for...
80
Respiratory Volumes
3.0K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
3.0K
Work Done During Volume Change
5.2K
In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process.
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
5.2K
