在美国,试管婴儿的效率下降
Norbert Gleicher1,2,3,4, Sonia Gayete-Lafuente1,2, Lara Guijarro-Baude1,5
1The Center for Human Reproduction, New York, NY, USA.
Human reproduction open
|February 9, 2026
概括
美国体外受精 (IVF) 周期效率在2012年至2021年间持续下降,尽管进行的周期数量有所增加. 这一趋势凸显了当前试管婴儿实践和附加使用的潜在问题.
科学领域:
- 生殖医学 生殖医学
- 在体外受精 (IVF) 的结果
- 公共卫生数据分析
背景情况:
- 以前的研究表明,IVF活产后活产率上升到2010年,随后下降.
- 这种下降可能与采用试管婴儿"补充"和不断变化的临床实践有关.
研究的目的:
- 调查2012年至2021年美国试管婴儿周期效率的趋势.
- 为了确定在此期间是否发生了IVF效率的下降.
主要方法:
- 一项回顾性队列研究,利用来自疾病预防控制中心 (2012-2021) 的公开可用的美国国家试管婴儿试管婴儿数据.
- 计算了每次开始周期的活产婴儿的试管婴儿治疗效率 (试管婴儿的治疗意图).
- 分析了关于试管婴儿周期开始,胚胎移植,胚胎储存和活产的数据.
主要成果:
- 在2012年至2021年期间,试管婴儿周期开始增加了234.7%,胚胎转移增加了150.3%,胚胎储存周期增加了902.3%.
- 在同一时期,活产儿数增加了179.2%.
- 然而,试管婴儿周期效率从2012年的29.1%线性下降到2021年的22.2%,相对减少了23.4%.
结论:
- 美国国家数据显示,从2012年到2021年,试管婴儿周期效率持续线性下降.
- 这种下降与胚胎储存和试管婴儿"附加"使用的增加有关.
- 这些发现需要对目前的试管婴儿临床实践和干预措施进行批判性重新评估.
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