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Updated: Feb 10, 2026

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
09:38

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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病例报告:一个患有罕见EGFR S768I/V769L化合物突变的患者从阿法替尼布和奥西默提尼布中受益

Qingli Cui1, Jiuzhou Zhao2, Yichen Ma3

  • 1Department of Integrated Traditional Chinese and Western medicine, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China.

Frontiers in pharmacology
|February 9, 2026
PubMed
概括

本案例研究检查了一名患有罕见EGFR S768I/V769L突变的非小细胞肺癌 (NSCLC) 的患者. 阿法替尼和奥西米尔替尼显示出临床活性,但需要改进的大脑透药物以获得更好的结果.

关键词:
在S768I和V769L中.亚法提尼布 (Afatinib) 是一种奥西米尔丁尼布 (osimertinib) 是一种这是一种罕见的EGFR突变.治疗治疗治疗治疗治疗治疗

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