相关实验视频

Updated: Feb 10, 2026

Intravital Imaging of Neutrophil Priming Using IL-1β Promoter-driven DsRed Reporter Mice
09:34

Intravital Imaging of Neutrophil Priming Using IL-1β Promoter-driven DsRed Reporter Mice

Published on: June 22, 2016

10.0K

氨酸激酶2抑制中性粒细胞的反应,促进病毒的持续性,同时减轻免疫病理

Vijayamahantesh Vijayamahantesh1, Ying He1, Lei Jiang2

  • 1Departments of Surgery and Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, United States.

Frontiers in immunology
|February 9, 2026
PubMed
概括

中性粒细胞中斯芬哥辛激酶2 (SphK2) 缺乏抑制慢性病毒感染期间的免疫病理. 缺少SphK2的中性粒细胞改善T细胞的反应,减少病毒载量和免疫疾病.

关键词:
调节T细胞的规则免疫抑制 免疫抑制中性粒细胞调节的调节斯芬戈氨酸激酶的作用病毒持久性 病毒持久性

更多相关视频

Live Imaging of Chemokine Receptors in Zebrafish Neutrophils During Wound Responses06:48

Live Imaging of Chemokine Receptors in Zebrafish Neutrophils During Wound Responses

Published on: December 4, 2020

2.8K
Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

11.0K

相关概念视频

Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
2.1K
Humoral Immune Responses01:36

Humoral Immune Responses

Overview
84.1K
Transcription Attenuation in Prokaryotes02:42

Transcription Attenuation in Prokaryotes

Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin structure.  Bacteria use these hairpins to regulate the transcription process and control the synthesis of several amino acids including histidine, lysine, threonine, and phenylalanine. Transcription attenuation takes place in the non-coding regions of mRNA.
There are several different mechanisms used to attenuate transcription. In ribosome mediated...
18.5K
Protein Kinases and Phosphatases02:54

Protein Kinases and Phosphatases

Proteins undergo chemical modifications that trigger changes in the charge, structure, and conformation of the proteins. Phosphorylation, acetylation, glycosylation, nitrosylation, ubiquitination, lipidation, methylation, and proteolysis are various protein modifications that regulate protein activity. Such modifications are usually enzyme-driven.
Protein kinases
Many proteins in the cell are regulated by phosphorylation, the addition of a phosphate group. A family of enzymes called kinases...
15.2K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
84.2K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
9.0K