乳腺癌患者的整体存活率:对27年历史队列的分析
Marina Elias Rocha1, Rosemar Macedo Sousa Rahal1, Leonardo Ribeiro Soares1
1Advanced Center for Breast Diagnosis (CORA), Federal University of Goiás, Goiânia, GO, Brazil.
这项研究分析了巴西戈亚尼亚的乳腺癌存活率,发现5年存活率为83.1%,并确定了影响预后的年龄和瘤亚型等因素.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 乳腺癌是全球和巴西的重大健康问题.
- 了解生存率和预后因素对于改善患者的治疗结果至关重要.
研究的目的:
- 分析总体存活率和确定乳腺癌的预后因素在巴西戈亚尼亚的27年历史女性队列中.
- 为特定的巴西人口提供有关乳腺癌趋势和结果的见解.
主要方法:
- 一项回顾性队列研究,利用戈亚尼亚人口癌症登记册 (1988-2015) 的数据.
- 卡普兰-梅尔生存分析和日志等级测试用于生存曲线的比较.
- 多变量考克斯回归分析以确定总生存率的预测因素.
主要成果:
- 总共有7,395名妇女被纳入;最常见的年龄组是50-69岁 (45.4%).
- 平均存活时间为122个月,5年和10年总生存率分别为83.1%和65.5%.
- 与生存率降低相关的因素包括年龄>70,组织学级III,雌激素/孕激素受体阴性状态,三阴性亚型和晚期疾病阶段.
结论:
- 该研究报告说,戈亚尼亚的乳腺癌患者的5年和10年整体生存率分别为83.1%和65.5%.
- 临床,生物学和与瘤相关的因素在这个人群中显著影响乳腺癌的预后.
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