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Updated: Feb 10, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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病理和突触功能在初级年龄相关病变中的区域相关性

Shrinath Kadamangudi1, Laura Sanchez-Sanchez1, Agenor Limon1,2

  • 1Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, Galveston, TX, USA.

Journal of Alzheimer's disease : JAD
|February 9, 2026
PubMed
概括

在初级与年龄相关的病 (PART) 中,海马中的聚合物将激发-抑制平衡转向抑制. 这种功能障碍与改变的囊泡运输通路有关,为早期病的机制提供了洞察力.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.激发与抑制 (E/I) 的比率.主要与年龄相关的病症 (PART)的寡合体是tau的寡合体.

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