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Updated: Feb 10, 2026

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高度血清性卵巢癌的单细胞空间图谱揭示了MHCII类作为空间瘤生态系统和临床结果的关键预测因素

Fernando Perez-Villatoro1, Aleksandra Shabanova1, Lilian van Wagensveld2

  • 1University of Helsinki Helsinki Finland.

Cancer discovery
|February 9, 2026
PubMed
概括

高度血清性卵巢癌 (HGSC) 瘤微环境的复杂性是由单细胞空间图谱揭示出来的. 瘤细胞MHCII表达预测延长存活时间,并增强CD8+T细胞活性,提供新的患者分层策略.

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