耐阻性高血压中的第一代和第二代巴罗反射激活装置的长期有效性和安全性:单一中心的回顾性分析
Jessica Kaufeld1, Ruha Younes1, Thomas Aper2
1Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Blood pressure
|February 9, 2026
概括
巴罗反射激活疗法 (BAT) 在耐性高血压中安全降低血压和心率. 较旧的Rheos®系统比较新的Barostim neoTM系统显示出更好的血压降低.
科学领域:
- 心血管医学 心血管医学
- 生物医学工程 生物医学工程
- 高血压管理 高血压管理
背景情况:
- 巴罗反射激活疗法 (BAT) 是一种基于设备的治疗耐性高血压的方法.
- 在第一代 (Rheos®) 和第二代 (Barostim neoTM) BAT系统之间存在有限的比较数据.
研究的目的:
- 为了比较Rheos®与Barostim neoTM在耐高血压患者中的疗效和安全性.
- 为了评估24小时门诊血压监测 (ABPM) 和心率 (HR) 在BAT世代之间的变化.
主要方法:
- 在2006年至2015年期间接受了BAT植入的54名患者的回顾性分析.
- 主要结果:设备几代之间24小时ABPM的变化.
- 二次结局:不良事件,MACE,功能和设备并发症.
主要成果:
- 在33名具有ABPM数据的患者中,BAT显著降低了24小时BP和HR.
- 莱奥斯 (Rheos®) 显示,24小时和夜间SBP显著减少.
- 巴罗斯蒂姆neoTM主要降低了HR,没有显著的BP降低.
结论:
- 在耐性高血压中降低BP和HR的BAT是安全有效的.
- 与第二代Barostim neoTM相比,第一代Rheos®表现出优异的降血压效果.
- 这些发现强调了电极设计,植入策略和患者选择对BAT有效性的重要性.
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