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儿童群体的视神经外皮直径:建立参考间隔和人体测量相关性
Mine Erkan1, Özlem Tolu Kendir1, Ramazan Gürlü2
1Akdeniz University Faculty of Medicine.
Pediatric emergency care
|February 9, 2026
概括
这项研究为4-18岁儿童建立了特定年龄的视神经外直径 (ONSD) 参考范围. 研究结果显示,随着年龄的增长,青少年的ONSD和BMI增加,有助于进行非侵入性内压力评估.
科学领域:
- 儿科神经学 儿科神经学
- 医疗成像医学成像
- 眼科医生 眼科 眼科
背景情况:
- 视神经外直径 (ONSD) 超声波是一种有前途的非侵入性工具,用于估计儿童的内压力 (ICP).
- 目前的临床使用受到健康儿科群体年龄特定规范数据缺乏的阻碍.
研究的目的:
- 在4至18岁的健康儿童中确定ONSD的特定年龄参考范围.
- 调查人类学因素 (包括BMI,身高和体重) 对该年龄组的ONSD测量的影响.
主要方法:
- 一项涉及150名健康儿童 (4-18岁) 的横截面研究,没有疑似增加的ICP或慢性疾病.
- 标准化轨道超声波被用于双边的ONSD测量.
- 计算了人体测量z-score,并建立了相关性和基于百分位数的参考间隔.
主要成果:
- 平均ONSD值为3.67±0.50毫米,较年长的儿童 (11-18岁) 的值明显高于较年轻的儿童 (4-10岁).
- 在整个队列中,ONSD与年龄,身高,体重和BMI有积极的相关性.
- 体重指数是ONSD的重要预测因素,特别是在青少年组 (11-18岁).
- 特定于年龄的第97百分点上限ONSD被确定为4.33毫米 (4-10岁) 和4.40毫米 (11-18岁).
结论:
- 这项研究为健康儿童的ONSD提供了关键的特定年龄的规范性参考间隔.
- 该研究强调了BMI对青少年ONSD测量的显著影响,这对于准确的ICP评估至关重要.
- 这些发现支持将ONSD超声波整合到儿科非侵入性ICP监测协议中,尽管建议进一步进行多中心验证.
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