Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Complement System01:27

Complement System

10.9K
The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
10.9K
Complementation Tests00:49

Complementation Tests

6.3K
A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
6.3K
Characteristics of Life01:23

Characteristics of Life

262.5K
Biology is a natural science that studies life and living organisms, including their structure, function, development, interactions, evolution, distribution, and taxonomy. The field's scope is extensive and divided into several specialized disciplines, such as anatomy, physiology, ethology, genetics, and many more. All living things share a few key traits, including cellular organization, heritable genetic material and the ability to adapt/evolve, metabolism to regulate energy needs, the...
262.5K
Phase Transitions: Sublimation and Deposition02:33

Phase Transitions: Sublimation and Deposition

20.3K
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
20.3K
Characteristics of Fluids01:20

Characteristics of Fluids

8.2K
When a force is applied parallel to the top surface of a solid, it resists the applied force due to the internal frictional forces between the layers of the solid known as shearing resistance. However, when the force is removed, the shearing forces restore the original shape of the solid. Other deformation forces also cause temporary changes in shape if the forces are not beyond a threshold magnitude. Solids tend to retain their shape, making the study of their rest and motion easier. Beyond...
8.2K
Characteristics of BJT01:17

Characteristics of BJT

1.3K
The Bipolar Junction Transistor (BJT), specifically in a common-emitter configuration, exhibits distinct current-voltage characteristics crucial for understanding its behavior in electronic circuits. These characteristics are established through experimental measurements of voltage and current relationships.
For input characteristics, the base-emitter voltage is varied, maintaining a constant collector-emitter voltage. This setup reveals a Shockley-type dependence of the collector current on...
1.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Interleukin 6 Receptor Blockade for Relapse Prevention in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

JAMA neurology·2026
Same author

Association of Cerebrospinal Fluid-Restricted Oligoclonal Bands With Relapsing Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

Pediatric neurology·2026
Same author

The impact of age on efficacy and safety of disease modifying treatment-insights from the Austrian Multiple Sclerosis Treatment Registry.

Journal of neurology·2026
Same author

Integration of retinal layer thinning into NEDA-3 predicts disability progression in multiple sclerosis.

Journal of neurology·2026
Same author

Comparative effectiveness of ocrelizumab in subgroups of patients with multiple sclerosis: a multi-registry observational cohort study.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

The gut microbiome in pediatric-onset acquired demyelinating syndromes by myelin oligodendrocyte glycoprotein antibody status.

Multiple sclerosis and related disorders·2026

相关实验视频

Updated: Feb 10, 2026

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43
07:47

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

Published on: October 23, 2018

9.7K

在NMOSD,MOGAD和MS中补体沉积的特征模式.

Yoshiki Takai1,2, Simon Hametner3, Christian Riedl3

  • 1Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. yoshiki.takai.e6@tohoku.ac.jp.

Acta neuropathologica
|February 9, 2026
PubMed
概括

在中枢神经系统炎症性脱髓化疾病中,补剂系统的激活不同. 神经脊髓炎光学谱系障碍表现出一致的沉积,而MOGAD和MS表现出不同的模式,反映出独特的疾病路径.

关键词:
C4d C4d 是一个词.这就是C9neo.补充 补充 补充 补充莫加德 - 莫加德在MSMSMSMSMSMSMSMSMSMSMS中,我们可以看到这是NMOSD的NMOSD.

更多相关视频

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management
08:09

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management

Published on: September 12, 2017

12.3K
Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition
06:30

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition

Published on: August 29, 2017

8.8K

相关实验视频

Last Updated: Feb 10, 2026

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43
07:47

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

Published on: October 23, 2018

9.7K
Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management
08:09

Measuring and Mapping Patterns of Soil Erosion and Deposition Related to Soil Carbonate Concentrations Under Agricultural Management

Published on: September 12, 2017

12.3K
Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition
06:30

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition

Published on: August 29, 2017

8.8K

科学领域:

  • 神经免疫学 神经免疫学
  • 病理学 病理学 病理学

背景情况:

  • 补体系统在中枢神经系统炎症性脱髓化疾病 (IDDs) 中发挥作用.
  • 它在氨酸寡腺细胞糖蛋白抗体相关疾病 (MOGAD) 和多发性硬化症 (MS) 的特定参与仍然不清楚,与神经髓炎光学谱障碍 (NMOSDs) 不同.

研究的目的:

  • 通过组织病理学评估补充系统参与NMOSD,MOGAD和MS.
  • 区分补充沉积在这些IDDs的致病性中的作用.

主要方法:

  • 免疫组织化学用于检查NMOSD,MOGAD和MS患者的中枢神经系统组织.
  • 对补充成分C4d,C3d和C9neo的沉积进行了分析,以分析损伤特征.

主要成果:

  • NMOSD在天体细胞的病变中显示出一种特征性的周血管补体沉积模式.
  • MOGAD显示了可变的C9neo沉积,区分A型 (保存的寡细胞) 和B型 (寡细胞损失).
  • 在周围斑块白质中,MS在髓层上显示了C4d沉积物,随着病变活动的减少而减少.

结论:

  • 在NMOSD,MOGAD和MS中明显的补充沉积模式表明了不同的潜在病原遗传机制.
  • 补充激活是这些中枢神经系统炎症性脱髓化疾病中特定的本病学相关的关键特征.