牙周炎与OSCC患者手术后传染性并发症之间的关联:一项回顾性研究
Chuqiao Xiao1, Qian Zhou1, Yichun Yang2
1State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
概括
牙周炎增加了接受手术的口腔癌患者手术部位感染和发烧的风险. 管理牙疾病可以改善口腔状细胞癌 (OSCC) 手术后的康复.
科学领域:
- 口腔瘤学 在口腔瘤学
- 牙周病学 牙周病学
- 外科手术的结果
背景情况:
- 牙周炎是口腔状细胞癌 (OSCC) 的已知危险因素.
- 牙周炎对OSCC患者手术后结果的影响尚不清楚.
研究的目的:
- 为了调查牙周炎严重程度和经过自由重建的OSCC患者的短期术后结果之间的关联.
主要方法:
- 对552名OSCC患者进行了回顾性研究.
- 根据CT扫描,将牙周炎分为没有,轻度和严重的类别.
- 用概括估计方程和多变量回归分析人口统计,手术细节,实验室结果和并发症.
主要成果:
- 严重的牙周炎显著增加了手术部位感染 (SSI) 和手术后发烧的风险.
- 牙周炎患者体温较高,发烧持续时间较长,感染标志物较高.
- 亚组分析显示,年轻患者,男性,吸烟者和没有糖尿病的患者的SSI风险增加.
结论:
- 牙周炎的严重程度与OSCC手术中的术后感染性并发症有关.
- 治疗牙周炎可能对改善OSCC患者的康复和治疗结果至关重要.
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