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Updated: Feb 10, 2026

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
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Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

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米托富素2通过抑制β-氨酸核转位来缓解肝脏纤维化

Chai-Ming Zeng1, Bin Shao2, Ling-Ling He1

  • 1Department of Geriatric Medicine, Fujian Key Laboratory of Geriatric Diseases, Fujian Provincial Center for Geriatrics, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China.

Current medical science
|February 9, 2026
PubMed
概括

米托素2 (MFN2) 通过阻断β-catenin,抑制非酒精性脂肪性肝病 (NAFLD) 的肝星细胞激活和肝纤维化. 这一发现强调了MFN2作为NAFLD相关肝纤维化的潜在治疗标.

关键词:
肝脏的星状细胞是什么脂肪毒性 脂肪毒性肝脏纤维化 肝脏纤维化与代谢功能障碍相关的脂肪性肝病 (MASLD)米托素 2 2 的使用.非酒精性脂肪肝炎 (NASH) 是一种非酒精性脂肪肝.在Wnt/β-catenin信号传输中.

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