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Updated: Feb 10, 2026

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通过SERPINE1驱动的MAPK激活,增强了结肠直肠癌中对质死的抵抗力和血管生成潜力

Piyao Gao1, Haoyang Li2, Jie Luo3,4

  • 1Department of Gastrointestinal Surgery, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning City, 530011, Guangxi Zhuang Autonomous Region, China.

Digestive diseases and sciences
|February 9, 2026
PubMed
概括

在结直肠癌 (CRC) 中SERPINE1的过度表达通过通过p38/MAPK通路增强血管生成和对亡的抗性来促进瘤生长. 这一发现为新的抗血管性CRC疗法提供了潜力.

关键词:
血管新生的产生.结肠直肠癌是一种癌症.这种疾病叫做cuproptosis.在P38/MAPK信号通道上.一个名为SERPINE1的小蛇.

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