在北极居民中肥胖发展的综合代谢指标因种族而异
Olga Sergeevna Vlasova1, Fatima Artyomovna Bichkaeva2, Alexandra Vitalievna Strelkova2
1N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences (FCIARctic UB RAS), Arkhangelsk, Arkhangelsk region, Russia. olgawlassova@mail.ru.
在俄罗斯北极地区,肥胖很常见,但土著男性的发病率较低. 虽然这两组都面临心脏代谢风险,但土著人口对肥胖的代谢后果不那么严重.
科学领域:
- 北极研究研究研究北极研究
- 人类生物学 人类生物学
- 公共卫生 公共卫生
背景情况:
- 肥胖和久坐不动的生活方式在全球范围内越来越令人担忧.
- 了解代谢健康的种族差异对于有针对性的干预至关重要.
研究的目的:
- 在俄罗斯北极地区的土著和高加索成年人之间比较肥胖发展的代谢参数变化.
- 评估久坐不动的生活方式对这些差异的影响.
主要方法:
- 身体质量指数 (BMI) 将参与者分为正常体重,超重和肥胖群体.
- 测量了胰岛素,脂肪酸 (FA) 和甘油三 (TG) 的水平.
- 计算了对胰岛素抵抗的恒温模型评估 (HOMA-IR).
主要成果:
- 肥胖与增加的TG和FA水平相关,并在女性中降低了HDL-C.
- 白人女性的葡萄糖水平较高,而白人男性的LDL-C水平较高.
- 胰岛素和HOMA-IR增加,更多的是白人,但土著妇女的FA,TG和葡萄糖水平较低.
结论:
- 超重和肥胖在俄罗斯北极地区的各个种族中普遍存在,除了土著男性的较低比例外.
- 肥胖与心脏代谢风险有关,特别是在两组女性中.
- 肥胖的代谢后果在土著人口中不那么明显,这表明潜在的选择性胰岛素耐药性.
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