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Updated: Feb 10, 2026

Depletion of Mouse Cells from Human Tumor Xenografts Significantly Improves Downstream Analysis of Target Cells
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Depletion of Mouse Cells from Human Tumor Xenografts Significantly Improves Downstream Analysis of Target Cells

Published on: July 29, 2016

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一种针对MERTK的抗体-药物结合物选择性地消耗M2瘤相关的巨细胞和表达MERTK的癌细胞

Shugaku Takeda1, Subhasree Sridhar2, Daniel Schefer1

  • 1Inspirna, Inc. United States.

Cancer research
|February 9, 2026
PubMed
概括

一种新型抗体-药物合物 (ADC) 针对MERTK的癌细胞和M2巨细胞,显示出优异的抗瘤疗效和没有视网膜毒性. 这种双重准的方法提高了癌症治疗的机会.

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