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相关概念视频

Spinal Cord01:26

Spinal Cord

2.0K
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
2.0K
The Spinal Cord01:54

The Spinal Cord

31.9K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
31.9K
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

3.6K
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
3.6K
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

5.9K
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
5.9K
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
916
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

4.9K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
4.9K

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相关实验视频

Updated: Feb 11, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

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在慢性椎脊髓压缩中MRI T2高强度,亡和神经炎症之间的相关性:子模型研究

Xingsheng Zhang1,2, Bingxuan Wu1, Tianhua Rong1

  • 1Department of Orthopaedic Surgery, Beijing Tiantan Hospital, Capital Medical University, No. 119 South 4th Ring West Road, Fengtai District, Beijing 100070,China.

Spine
|February 9, 2026
PubMed
概括
此摘要是机器生成的。

在慢性椎脊髓压缩中,MRI T2高强度表明细胞亡和NLRP3炎症增加. 这表明信号强度比可能是退行性宫髓病变 (DCM) 病理学的生物标志物.

关键词:
退行性子宫髓病变 退行性子宫髓病变磁力共振成像信号的强度.在NLRP3炎症酶组中,动物模型动物模型灭症 (apoptosis) 是一种死亡的过程.神经炎症是一种神经炎症.

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Calibrated Forceps Model of Spinal Cord Compression Injury
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相关实验视频

Last Updated: Feb 11, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

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Calibrated Forceps Model of Spinal Cord Compression Injury

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科学领域:

  • 神经科学是一个神经科学.
  • 放射学 放射学是一门学科.
  • 病理学 病理学 病理学

背景情况:

  • T2加权的MRI超强度在退行性宫骨髓病 (DCM) 中很常见,但其病理基础尚不清楚.
  • 细胞亡和神经炎症是DCM病变发生的关键因素,但它们与MRI发现的联系需要系统研究.

研究的目的:

  • 调查MRI T2加权信号强度变化与子模型中慢性椎脊髓压缩中的apoptotic/神经炎症机制之间的相关性.

主要方法:

  • 使用了慢性椎脊髓压缩的子模型,与控制,轻度和重度压缩的组进行了组合.
  • 评估包括6个月的运动功能,体感唤起潜力 (SEP) 和MRI信号强度比 (SCR).
  • 脊髓组织分析涉及TUNEL测定,免疫光学和西部抹迹,用于细胞亡和炎症标志物.

主要成果:

  • 压缩严重程度与功能缺陷和延长的SEP延迟相关.
  • 观察到SCR升高和TUNEL阳性细胞增加,压缩更大.
  • 在SCR和亡标志物 (Bax/Bcl-2比率) 和NLRP3介导的炎症之间发现了强烈的正相关性.

结论:

  • 慢性椎脊髓压缩中的MRI T2高强度与神经元亡和NLRP3炎症的严重程度显著相关.
  • 信号强度比 (SCR) 可能作为一种定量成像生物标志物,用于退行性宫髓病变 (DCM) 的病理变化.