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Updated: Feb 11, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

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Published on: March 2, 2014

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选择性向免疫检查点HLA-G和CD47使用新型双信号蛋白DSP216促进先天抗癌免疫力

Lisa J Jacob1, Liat Tamir2, Mufeed Abdeen2

  • 1Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 9, 2026
PubMed
概括

一种新的免疫疗法,双信号蛋白216 (DSP216),针对CD47和HLA-G检查点. 这种双重作用的免疫检查点抑制剂 (ICI) 在临床前研究中显示出它有望通过选择性向癌细胞来增强癌症治疗.

关键词:
CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47 CD47在HLA-G中,HLA-G是最常见的.这就是LILRB1的原因.这就是LILRB2的原因.这就是SIRPα.免疫检查点的检查点.免疫疗法 免疫疗法

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