皮肤上皮质性淋巴瘤与明显的核形在一只狗
Da-Hyeon Lee1, Woo-Jin Song2, Jongtae Cheong3
1College of Veterinary Medicine, Jeju National University, Jeju 63243, Korea.
Journal of veterinary science
|February 9, 2026
概括
这份病例报告详细介绍了一种罕见的狗皮上皮质性淋巴瘤 (CEL),其异常的细胞特征模仿了其他癌症. 需要进一步的研究来了解这种非典型的犬类淋巴瘤表现.
科学领域:
- 兽医病理学 兽医病理学
- 狗类瘤学 狗类瘤学
- 皮肤病学 皮肤病学
背景情况:
- 皮肤上皮质性淋巴瘤 (CEL) 是狗的一种罕见癌症.
- 不典型的表现,包括不寻常的细胞形状和免疫标记,很少被记录下来.
研究的目的:
- 描述了一种罕见的犬类CEL病例,具有显著的细胞形.
- 突出非典型的CEL形态所带来的诊断挑战.
主要方法:
- 一只患有口腔和皮肤病变的黄金回归犬接受了细针吸血和组织病理学.
- 用于抗原受体重排的流细胞计和PCR用于免疫类型和克隆性评估.
主要成果:
- 细胞学表明圆细胞瘤,如淋巴瘤或乳腺癌.
- 组织病理学证实了CEL;流细胞计揭示了CD5+T细胞表型;PCR显示T细胞受体的玛-三角形克隆性.
结论:
- 这一案例证明了狗CEL的非典型临床病理特征.
- 这些发现强调了先进诊断对于准确诊断和了解疾病生物学的重要性.
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