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Updated: Feb 11, 2026

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通过调节UU/UA-dinucleotide丰富的转录丰度,RNase L抑制剂ABCE1对癌症转录组进行了深刻的改变

Edward Hitti1, Tala Bakheet1, Linah Mahmoud1

  • 1Molecular BioMedicine Department, Research and Innovation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

RNA biology
|February 9, 2026
PubMed
概括

一种RNase L抑制剂ABCE1的过度表达改变了癌症转录组,影响了结直肠和肺癌的细胞增殖和患者存活率. 结直肠癌中高的ABCE1水平与改善的生存率相关,这与肺癌发现相反.

关键词:
在ABCE1中,ABCE1是ABCE1.在 RNase L 中,UU/UA 双核化物结肠直肠腺癌细胞瘤肺部腺癌的癌症.

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