连接肺和牙:慢性阻塞性肺病中牙周炎患病率和严重程度的元分析
Gowri Sivaramakrishnan1, Kannan Sridharan2
1Bahrain Defence Force Royal Medical Services, Riffa, Bahrain. Gowri.sivaramakrishnan@gmail.com.
BDJ open
|February 9, 2026
概括
患有慢性阻塞性肺病 (COPD) 的患者患有牙周炎的患病率更高. 这次元分析发现,COPD患者的牙周破坏增加,但证据确定性较低,需要进一步研究.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 牙周病学 牙周病学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 是一种慢性炎症和空气流量限制的慢性呼吸道疾病.
- 牙周炎是一种常见的牙疾病,与COPD具有共同的风险因素,特别是吸烟.
- 了解这些疾病之间的联系对于全面的患者护理至关重要.
研究的目的:
- 评估COPD诊断患者牙周炎的患病率和严重程度.
- 评估关键牙周参数,包括COPD患者的探针深度 (PD),临床附着损失 (CAL) 和探针出血 (BOP).
主要方法:
- 一项系统的文献搜索确定了41项符合COPD和牙周炎的纳入标准的研究.
- 使用RAYYAN提取数据,并使用纽卡斯尔-太华尺度 (NOS) 评估研究质量.
- 进行了随机效应的元分析,进行了异质性,敏感性和出版偏差分析.
主要成果:
- 在35%的COPD患者中存在牙周炎,明显高于对照组.
- 慢性肺炎患者的CAL (0.68 [0.37;0.98]),PD (0.72 [0.12; 1.31]) 和BOP (1.49 [0.19;2.79]) 的增加.
- 支持这些发现的证据的确定性被评为低至非常低.
结论:
- 慢性肺炎患者患牙周炎的患病率较高,牙周健康状况较差.
- 虽然建议有关联,但证据的确定性较低,需要谨慎解释.
- 需要高质量的前性研究来证实这种关系并指导临床实践.
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