用双层嵌入和三层解释来进行第三阶段NSCLC的智能MDT治疗决策
Ziyu Chen1, Naijie Chai2, Jianqiang Wang3
1College of Management, Xi'an University of Science and Technology, Xi'an, 710054, PR China.
Scientific reports
|February 9, 2026
概括
一个可解释的AI模型有助于推第三阶段非小细胞肺癌 (NSCLC) 的治疗方法. 与AI模型一致的治疗方法相比,与非一致的治疗方法相比,显著提高了患者的存活率.
科学领域:
- 在瘤学瘤学.
- 人工智能的人工智能
- 医疗信息学 医疗信息学
背景情况:
- 第三阶段非小细胞肺癌 (NSCLC) 治疗由于患者异质性而复杂.
- 多学科团队 (MDT) 提供个性化护理,但面临实际限制.
- 需要有效和可解释的治疗推系统.
研究的目的:
- 开发一种可解释的AI方法,用于在NSCLC的第三阶段智能MDT治疗建议.
- 增强临床文本表示和治疗建议的解释性.
- 评估模型的性能及其与患者生存结果的关联.
主要方法:
- 使用双层嵌入技术捕获本地和全球文本信息.
- 采用注意力流和注意力机制来确定治疗建议中的关键因素.
- 在第三阶段NSCLC治疗建议的准确性,精度,回忆和F1得分方面实现了超过85%的绩效指标.
主要成果:
- 拟议的模型在推第三阶段NSCLC治疗方面表现出很高的性能.
- 接受模型一致治疗的患者显示显著改善了1,3年和5年生存率.
- 卡普兰-梅尔生存曲线证实了与模型一致的治疗方法的生存益处.
结论:
- 可解释的人工智能模型为复杂的NSCLC治疗决策提供了实际解决方案.
- 以模型为指导的治疗建议与患者生存率的提高有关.
- 该研究验证了模型的结构及其对临床结果的积极影响.
更多相关视频
相关概念视频
Leveling Effect
1.4K
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K
High-Level and Low-Level Awareness
786
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
786
Levels of Organization
141.6K
Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
141.6K
Fermi Level
1.9K
The Fermi-Dirac function is represented by an S-shaped curve indicating the probability of an energy state being occupied by an electron at a given temperature. The Fermi level is the energy level at which there is a fifty percent chance of finding an electron, and it is positioned between the lower-energy valence band and the higher-energy conduction band.
At absolute zero temperature, electrons fill all energy states up to the Fermi level, leaving upper states empty. As the temperature rises,...
At absolute zero temperature, electrons fill all energy states up to the Fermi level, leaving upper states empty. As the temperature rises,...
1.9K
Introduction and Methods of Leveling
532
Leveling is a surveying procedure used to determine elevation differences between distant points. Elevation refers to the vertical distance above or below a reference datum, typically mean sea level (MSL). In the United States, elevations are often referenced to the mean sea level station at Father Point Rimouski along the St. Lawrence Seaway. To make the datum accessible, permanent markers are established throughout the region. These markers, called benchmarks, have known elevations. If the...
532
Ratio Level of Measurement
21.6K
The way a set of data is measured is called its level of measurement. Correct statistical procedures depend on a researcher being familiar with levels of measurement. For analysis, data are classified into four levels of measurement—nominal, ordinal, interval, and ratio.
A set of data measured using the ratio scale takes care of the ratio problem and provides complete information. Ratio scale data are like interval scale data, except they have a zero point and ratios can be calculated....
A set of data measured using the ratio scale takes care of the ratio problem and provides complete information. Ratio scale data are like interval scale data, except they have a zero point and ratios can be calculated....
21.6K


