针对复发性急性和慢性胰腺炎患者的疼痛管理的数字认知行为疗法 (IMPACT-2):混合有效性实施试验研究协议
Tonya M Palermo1,2, Olivia Ohls3, Blake Dear4
1Department of Anesthesiology & Pain Medicine, University of Washington School of Medicine, Seattle, USA. tonya.palermo@seattlechildrens.org.
Trials
|February 10, 2026
概括
数字认知行为疗法 (CBT) 显示出治疗慢性胰腺炎疼痛的前景. 这项试验将测试其有效性,并为可访问的疼痛自我管理的未来实施提供信息.
科学领域:
- 胃肠病学 胃肠病学
- 疼痛管理 疼痛管理
- 数字健康数字健康
背景情况:
- 腹痛是高达90%的复发性急性胰腺炎 (RAP) 和慢性胰腺炎 (CP) 患者的主要症状.
- 增加疼痛的严重程度和频率与显著的发病率相关,包括抑郁症,焦虑症,减少身体功能,睡眠障碍和生活质量下降.
- 一项试点研究表明,数字认知行为疗法 (CBT) 在缓解RAP和CP的成年人疼痛和残疾方面的初步疗效.
研究的目的:
- 为了评估数字CBT在治疗慢性疼痛的有效性,在成年人有复发性急性或慢性胰腺炎.
- 为可扩展的数字CBT干预收集实施数据.
主要方法:
- 一个多站点的实用临床试验,涉及280名成年人 (18+) 患有RAP或CP经历慢性疼痛.
- 参与者被随机分配到数字CBT (胰腺炎疼痛课程) 或数字疼痛教育.
- 评估是在基线,2个月和6个月进行的,主要结果是疼痛干扰和严重程度.
主要成果:
- 这个部分不在所提供的摘要中.
- 这个部分不在所提供的摘要中.
结论:
- 该IMPACT-2试验旨在推进RAP和CP的非药物疼痛管理解决方案.
- 成功的发现将解决对低成本,可访问的疼痛自我管理策略的需求.
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