作为治疗性siRNA传递系统,Carbosilane Dendrimers的血相容性可以跨越血脑屏障

Serafin Zawadzki1,2, Simon Suty3, Elżbieta Okła1

  • 1Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska St., Lodz 90-236, Poland.

PubMed
概括

这项研究评估了一种用于阿尔茨海默病治疗的新型纳米载体的血红相容性. PEGylated carbosilane dendrimer及其 dendriplex对血液成分的不良影响最小,支持它们的临床潜力.

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