韩国患有抑郁症的儿童和青少年中非典型抗精神病药物的使用趋势
Kee Jeong Park1, Ye-Jee Kim2, Eunji Jung3
1Department of Psychiatry, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Journal of Korean medical science
|February 10, 2026
概括
韩国青年患有抑郁症的非典型抗精神病药物 (AAP) 处方从2010年到2022年显著增加,特别是对于那些患有并发症的人来说. 阿里皮普拉现在是最常见的AAP.
科学领域:
- 儿童精神病学 儿童精神病学
- 心理药理学 心理药理学
- 公共卫生 公共卫生
背景情况:
- 非典型抗精神病药物 (AAP) 越来越多地被用于治疗儿科抑郁症.
- 在患有抑郁症的儿童和青少年中,非标签使用AAP很常见.
- 在韩国患有抑郁症的年轻人中研究了AAP处方的纵向趋势和模式.
研究的目的:
- 分析韩国儿童和青少年被诊断患有抑郁症的非典型抗精神病药物 (AAP) 处方的纵向趋势.
- 检查2010年至2022年期间该人口中AAP使用的模式.
- 为了确定与儿童抑郁症中AAP处方相关的因素.
主要方法:
- 使用韩国国家健康保险审查和评估服务数据 (2010-2022) 的基于人口的研究.
- 每年进行横截面评估,以追踪0-18岁抑郁症患者AAP处方的纵向趋势.
- 分析2022年的数据,以确定当前的处方模式.
主要成果:
- 针对儿科抑郁症的AAP处方从2010年的10.4%增加到2022年的40.0% (年增长14.9%).
- 患有精神病并发症的患者,特别是注意力缺陷多动性障碍患者的处方率更高.
- 处方模式从RISPERIDONE转向ARIPIPRAZOLE,ARIPIPRAZOLE是2022年最常被处方的药物之一.
结论:
- 非典型抗精神病药物的使用在患有抑郁症的韩国儿童和青少年中显著增加,特别是那些患有并发症的儿童和青少年.
- 为了开发更安全,基于证据的AAP治疗儿科抑郁症,进一步的研究是必不可少的.
- 这些发现强调了需要仔细考虑在这个脆弱人群中使用AAP的必要性.
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