针对急性角膜水滴的三个手术方法的治疗结果
Jie Bai1,2, Shaowei Li1,2,3, Chang Liu1,2
1Department of Cornea, Beijing Aier-Intech Eye Hospital, Beijing, China.
概括
用空气注入的压缩 (CSAI) 为急性角膜水 (ACH) 提供分阶段治疗,并结合深前层叶片角膜整形术 (DALK),提供平衡的视觉结果和降低排斥风险. 穿透性角膜整形 (PKP) 提供了更好的视力,但风险更高.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 视觉科学 视觉科学 视觉科学
背景情况:
- 急性角膜水 (ACH) 是一种危及视力的疾病.
- 手术的目的是恢复角膜的完整性和视觉功能.
- 对比不同手术方法的结果对于治疗优化至关重要.
研究的目的:
- 为了比较急性角膜水 (ACH) 三种手术方法的治疗结果.
- 评估的方法包括用室内空气注射 (CSAI) 进行压缩,CSAI随后进行深部前层层叶片角膜整形 (DALK) 和穿透角膜整形 (PKP).
主要方法:
- 一项涉及26名患者 (26只眼睛) 的研究分为三个组:CSAI-only (7只眼睛),CSAI+DALK (14只眼睛) 和PKP (5只眼睛).
- 收集的数据包括人口统计,视力敏度 (BCVA),角膜,中角膜厚度 (CCT),角膜曲率,分辨时间和并发症.
主要成果:
- 单独使用CSAI,导致平均胀解脱时间约为2周,视觉改善有限.
- 术后的BCVA在所有组都得到改善 (p < 0.05),其中PKP显示最佳BCVA (0.15 ± 0.09 logMAR),其次是CSAI+DALK (0.34 ± 0.16 logMAR) 和仅CSAI (0.60 ± 0.15 logMAR).
- 在DALK计划的17个眼睛中,Descemet的膜穿孔发生在5个眼睛中;一个PKP病例经历了移植排斥.
结论:
- CSAI有效地缩短了 ACH 持续时间,但提供了适度的视觉效果,作为初始治疗阶段.
- CSAI跟着DALK (CSAI+DALK) 显著增强BCVA,降低移植器的排斥率,提供了一个有利的治疗选择.
- PKP提供了最高的BCVA,但与排斥风险增加有关,使其适用于对其他方法无反应的病例.
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