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Updated: Feb 11, 2026

Amplicon Sequencing using the Long-Read Sequencing Technologies
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Amplicon Sequencing using the Long-Read Sequencing Technologies

Published on: August 29, 2025

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长读数测序在检测大多数结构变异方面优于短读数测序

Xinyue Chen1, Xiaodong Lu2, Xianglin Shi2

  • 1Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

Serican journal of medicine
|February 10, 2026
PubMed
概括

长读测序 (LRS) 在检测癌症基因组中的插入和小删除等结构变异 (SV) 中表现出色. 短读序列 (SRS) 对于长期删除仍然有用,但LRS在SV检测中提供了更高的精度和更少的错误.

关键词:
长时间阅读序列排序.简读序列的短阅读序列.结构变化的结构变化.进行全基因组测序.

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