当药物损害肌肉时:一个十几岁的青少年患有急性肌肉分裂的病例
Sari Aidek1, Khalid Ibrahim2, Mohamed Alaqqad3
1Orthopaedics, Dubai Health, Dubai, ARE.
Cureus
|February 10, 2026
概括
伊索特里诺因可以引起狂犬病,这是一个严重的疾病,特别是运动. 早期识别和治疗对于恢复和预防损伤等并发症至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 毒理学 毒理学 毒理学
- 肌肉骨医学 肌肉骨医学
背景情况:
- 拉布地质溶解是一种罕见但严重的异二醇治疗不良反应.
- 剧烈的体力活动可能会增加与异二因相关的狂犬病溶解的风险.
- 药物诱导的肌肉衰竭可能导致严重的并发症.
研究的目的:
- 报告药物诱导的狂犬病溶解与二次肌内的病例,该病例发生在接受异氨酸治疗的青少年中.
- 要强调认识到这种不良影响在身体活跃的患者中的重要性.
- 强调及时诊断和管理,以获得最佳的结果.
主要方法:
- 一个16岁的男性接受异丁治疗的案例介绍.
- 临床评估,包括病史上的疼痛,发烧和最近的强烈体力活动.
- 实验室检查 (炎症标志物,肌激酶,肌球蛋白尿) 和磁共振成像 (MRI) 用于诊断.
- 治疗包括补水,抗生素,停用异丁,以及手术排水.
主要成果:
- 患者出现了脏和大腿疼痛,发烧,炎症标志物升高,肌酸酶和肌球蛋白尿.
- 核磁共振扫描显示了广泛的肌肉炎与多个肌肉内和肌肉间.
- 成功的治疗导致完全康复,没有损伤.
结论:
- 与伊索特里诺因相关的拉布多溶解是一种严重的疾病,需要迅速识别,特别是在活跃的个体中.
- 通过临床怀疑,实验室检查和成像检查进行早期诊断至关重要.
- 及时干预,包括戒药和适当的医疗/外科管理,可以改善患者的治疗结果,并预防严重的并发症.
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