我们的操作是否变得更聪明? 危险的恶性病症跨贝塞斯达类别-一个10年的机构经验
Shawn Joseph Thadathil1, Karunya Gopal Rajagopal1, Iona Leekha Mathew2
1Department of Head and Neck Surgical Oncology, VPS Lakeshore Hospital and Research Centre, Kochi, India.
Head & neck
|February 10, 2026
概括
使用贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 的甲状腺癌风险分层显示,在不确定的类别 (III-V) 中,恶性瘤的发病率高于估计. 这些数据有助于临床决策,特别是当分子测试不可用时.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 细胞病理学 细胞病理学
背景情况:
- 全球甲状腺癌发病率正在上升,与甲状腺结节检测增加有关.
- 这种增加引发了人们对过度诊断和过度治疗的担忧.
- 贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 有助于风险分层,但不确定的类别 (III-V) 带来了挑战,特别是在没有分子测试的情况下.
研究的目的:
- 在接受甲状腺手术的印度患者中,评估每个TBSRTC类别的恶性瘤 (ROM) 风险.
- 将这些ROM率与2023年TBSRTC风险估计进行比较.
主要方法:
- 细针吸收细胞学和组织病理学数据 (2014-2024) 的回顾性分析.
- 计算每个TBSRTC类别的ROM.
- 计算的ROM与已建立的TBSRTC风险估计进行比较.
主要成果:
- TBSRTC VI显示了100%的恶性瘤率.
- 与TBSRTC估计 (22%, 30%, 74%) 相比,在TBSRTC III (58.7%),IV (82.7%) 和V (100%) 中观察到明显更高的恶性瘤率.
- 核TBSRTC III (70.0%) 的恶性瘤发病率高于其他TBSRTC III (40.57%).
结论:
- 机构特定的恶性瘤数据提高了TBSRTC的临床实用性.
- 增强数据有助于患者咨询,特别是在资源有限的环境中.
- 当局数据对于准确的甲状腺癌风险评估至关重要,当分子诊断无法使用时.
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